|
|
putrescine + S-adenosylmethioninamine <=> H+ + spermidine + S-methyl-5''-thioadenosine
|
2.5.1.104
N1-aminopropylagmatine synthase
2.5.1.16
spermidine synthase
2.5.1.23
sym-norspermidine synthase
|
–
–
–
|
| |
BRENDA:
BR47664
KEGG:
R01920
MetaCyc:
SPERMIDINESYN-RXN
SABIO-RK:
1974
|
|
|
|
carboxynorspermidine + NADP+ + H2O <=> L-aspartate_4-semialdehyde + 1,3-diaminopropane + NADPH + H+
|
1.4.1.B4
1.5.1.43
carboxynorspermidine synthase
|
–
–
|
| |
BRENDA:
BR49680
KEGG:
R09080
MetaCyc:
RXN-11565
SABIO-RK:
14726
|
|
|
|
H+ + carboxynorspermidine <=> norspermidine + CO2
|
4.1.1.96
carboxynorspermidine decarboxylase
|
–
|
| |
BRENDA:
BR50201
KEGG:
R09082
MetaCyc:
RXN-9380
|
|
|
|
S-adenosylmethioninamine + norspermidine <=> S-methyl-5''-thioadenosine + norspermine + H+
|
2.5.1.104
N1-aminopropylagmatine synthase
2.5.1.126
norspermine synthase
2.5.1.127
caldopentamine synthase
|
–
–
–
|
| |
BRENDA:
BR51119
KEGG:
R11088
MetaCyc:
RXN-15698
SABIO-RK:
14205
|
|
|
|
H+ + L-2,4-diaminobutanoate <=> 1,3-diaminopropane + CO2
|
4.1.1.17
ornithine decarboxylase
4.1.1.18
lysine decarboxylase
4.1.1.86
diaminobutyrate decarboxylase
|
–
–
–
|
| |
BRENDA:
BR48691;
BS453453
KEGG:
R07650
MetaCyc:
4.1.1.86-RXN
|
|
|
|
S-adenosylmethioninamine + N4-aminopropylspermidine <=> S-methyl-5''-thioadenosine + N4-bis(aminopropyl)spermidine + H+
|
2.5.1.128
N4-bis(aminopropyl)spermidine synthase
|
–
|
| |
BRENDA:
BR51125
KEGG:
R11160
MetaCyc:
RXN-15865
|
|
|
|
acetyl-CoA + spermidine <=> N1-acetylspermidine + H+ + CoA
|
2.3.1.57
diamine N-acetyltransferase
|
–
|
| |
BRENDA:
BS321083
MetaCyc:
SPERMACTRAN-RXN
SABIO-RK:
7731
|
|
|
|
H2O + agmatine <=> Urea + putrescine
|
3.5.3.1
arginase
3.5.3.11
agmatinase
|
–
–
|
| |
BRENDA:
BR26108
KEGG:
R01157
MetaCyc:
AGMATIN-RXN
SABIO-RK:
595
|
|
|
|
N1-acetylspermine + O2 + H2O <=> N1-acetylspermidine + 3-aminopropionaldehyde + H2O2
|
1.5.3.16
spermine oxidase
|
–
|
| |
BRENDA:
BS259328
MetaCyc:
POLYAMINE-OXIDASE-RXN
|
|
|
|
acetyl-CoA + spermine <=> N1-acetylspermine + CoA + H+
|
2.3.1.57
diamine N-acetyltransferase
|
–
|
| |
BRENDA:
BS321086
MetaCyc:
RXN-9939
SABIO-RK:
7729
|
|
|
|
H+ + N-Carbamoylputrescine + H2O <=> putrescine + CO2 + NH3
|
3.5.1.53
N-carbamoylputrescine amidase
|
–
|
| |
BRENDA:
BR22697
KEGG:
R01152
MetaCyc:
N-CARBAMOYLPUTRESCINE-AMIDASE-RXN
SABIO-RK:
1393
|
|
|
|
putrescine + L-glutamate + ATP <=> H+ + gamma-L-glutamylputrescine + ADP + phosphate
|
6.3.1.11
glutamate---putrescine ligase
|
–
|
| |
BRENDA:
BR48542
KEGG:
R07414
MetaCyc:
RXN0-3901
|
|
|
|
carboxyspermidine + H+ <=> spermidine + CO2
|
4.1.1
4.1.1.96
carboxynorspermidine decarboxylase
|
–
–
|
| |
BRENDA:
BR50202
KEGG:
R09081
MetaCyc:
RXN-11564
|
|
|
|
gamma-L-glutamylputrescine + H2O + O2 <=> gamma-glutamyl-gamma-aminobutyraldehyde + H2O2 + NH3
|
1.4.3
1.4.3.B1
1.4.3.M3
|
–
–
–
|
| |
BRENDA:
BR51104
KEGG:
R07415
MetaCyc:
RXN0-3921
|
|
|
|
S-adenosylmethioninamine + spermidine <=> S-methyl-5''-thioadenosine + N4-aminopropylspermidine + H+
|
2.5.1.128
N4-bis(aminopropyl)spermidine synthase
|
–
|
| |
BRENDA:
BR51124
KEGG:
R11159
MetaCyc:
RXN-15864
|
|
|
|
4-(glutamylamino)_butanoate + H2O <=> L-glutamate + 4-aminobutanoate
|
3.5.1.94
gamma-glutamyl-gamma-aminobutyrate hydrolase
|
–
|
| |
BRENDA:
BR48700
KEGG:
R07419
MetaCyc:
RXN0-3942
|
|
|
|
gamma-glutamyl-gamma-aminobutyraldehyde + NADP+ + H2O <=> 4-(glutamylamino)_butanoate + NADPH + H+
|
1.2.1.99
4-(gamma-glutamylamino)butanal dehydrogenase
|
–
|
| |
BRENDA:
BR49659
KEGG:
R07418
MetaCyc:
RXN0-3922
|
|
|
|
agmatine + S-adenosylmethioninamine <=> N1-aminopropylagmatine + S-methyl-5''-thioadenosine + H+
|
2.5.1.104
N1-aminopropylagmatine synthase
|
–
|
| |
BRENDA:
BR50430
KEGG:
R10338
MetaCyc:
RXN-12514
SABIO-RK:
14103
|
|
|
|
spermidine + S-adenosylmethioninamine <=> H+ + spermine + S-methyl-5''-thioadenosine
|
2.5.1.104
N1-aminopropylagmatine synthase
2.5.1.16
spermidine synthase
2.5.1.22
spermine synthase
2.5.1.23
sym-norspermidine synthase
2.5.1.79
thermospermine synthase
|
–
–
–
–
–
|
| |
BRENDA:
BR44280
KEGG:
R02869
MetaCyc:
SPERMINE-SYNTHASE-RXN
SABIO-RK:
2733
|
|
|
|
H+ + L-arginine <=> CO2 + agmatine
|
4.1.1.19
arginine decarboxylase
|
–
|
| |
BRENDA:
BR279
KEGG:
R00566
MetaCyc:
ARGDECARBOX-RXN
SABIO-RK:
594
|
|
|
|
H+ + L-ornithine <=> CO2 + putrescine
|
4.1.1.17
ornithine decarboxylase
4.1.1.18
lysine decarboxylase
4.1.1.19
arginine decarboxylase
4.1.1.86
diaminobutyrate decarboxylase
4.1.1.B12
|
–
–
–
–
–
|
| |
BRENDA:
BR277
KEGG:
R00670
MetaCyc:
ORNDECARBOX-RXN
SABIO-RK:
1050
|
|
|
|
S-adenosylmethioninamine + norspermine <=> S-methyl-5''-thioadenosine + caldopentamine + H+
|
2.5.1.126
norspermine synthase
2.5.1.127
caldopentamine synthase
|
–
–
|
| |
BRENDA:
BR51120
KEGG:
R11089
MetaCyc:
RXN-15699
|
|
|
|
1,3-diaminopropane + S-adenosylmethioninamine <=> norspermidine + H+ + S-methyl-5''-thioadenosine
|
2.5.1.104
N1-aminopropylagmatine synthase
2.5.1.126
norspermine synthase
2.5.1.127
caldopentamine synthase
2.5.1.23
sym-norspermidine synthase
|
–
–
–
–
|
| |
BRENDA:
BR47539
KEGG:
R03271
MetaCyc:
SYM-NORSPERMIDINE-SYNTHASE-RXN
SABIO-RK:
3092
|
|
|
|
carboxyspermidine + H2O + NADP+ <=> L-aspartate_4-semialdehyde + putrescine + NADPH + H+
|
1.4.1.B4
1.5.1.43
carboxynorspermidine synthase
|
–
–
|
| |
BRENDA:
BR50244
KEGG:
R09079
MetaCyc:
RXN-11566
|
|
|
|
N1-aminopropylagmatine + H2O <=> spermidine + Urea
|
3.5.3.24
N1-aminopropylagmatine ureohydrolase
|
–
|
| |
BRENDA:
BR50461
KEGG:
R10347
MetaCyc:
RXN-12515
|
|
|
|
H2O + agmatine <=> NH3 + N-Carbamoylputrescine
|
3.5.3.12
agmatine deiminase
|
–
|
| |
BRENDA:
BR22722
KEGG:
R01416
MetaCyc:
AGMATINE-DEIMINASE-RXN
SABIO-RK:
1603
|
|
